Fig. 2: Spatial mapping of SNP-based heritability and genetic correlation estimates obtained using MGREML (N = 20,190) of relative gray matter volumes in different cortical and subcortical brain areas.
From: Multivariate analysis reveals shared genetic architecture of brain morphology and human behavior
a SNP-based heritability of relative gray matter volume mapped to the respective brain region in three dimensions. Each dot represents an area, the color and size represent the heritability of that area. b SNP-based heritability and standard error of relative gray matter volume of each brain region grouped by global anatomical area. c Genetic correlations between the cortical and subcortical relative gray matter volumes. The opacity and color represent the strength of the genetic overlap between these two areas (blue vertices represent a negative correlation, red vertices a positive correlation). Only genetic correlations larger than |0.25| are shown. d Average genetic correlations in broad anatomical areas of the brain.
