Fig. 1: The alteration in the genetic diversity of native gut microbiome due to probiotic intervention.

a The barplot indicates the number of gut resident species that had SNVs after probiotic intake. The bars represent the number of species that had SNVs. b The scatter plot shows the correlation between the raw number of SNVs and the sequencing depth of the target genomes. Green represents the mice (R = 0.66, P = 0.003), while orange represents the human cohort (R = 0.69, P < 0.001). c The barplot indicates the normalized number of SNVs identified in two time points (baseline and end point of probiotic intervention in each study). All error bars represent the SEM. The source data for graphs are available as Supplementary Data 7 or FigShare (https://figshare.com/projects/Probiotic_consumption_influences_universal_adaptive_mutations_in_indigenous_human_and_mouse_gut_microbiota/122447).