Table 1 Patient characteristics in the three gene expression clusters.
|  | All (n = 137) | 1(n = 35) | 2(n = 52) | 3(n = 50) | p-values* |
|---|---|---|---|---|---|
AGE | |||||
Mean+/−sd | 3.99+/−2.89 | 2.91+/−2.29 | 4.1+/−3.42 | 4.62+/−2.46 |  |
Median (IQR) | 3 (2, 5) | 2 (1,4) | 3 (2,5) | 4 (3,6) | 0.001 |
SEX, n (%) | |||||
Female | 57 (41.61%) | 8 (22.86%) | 25 (48.08%) | 24 (48%) | Â |
Male | 80 (58.39%) | 27 (77.14%) | 27 (51.92%) | 26 (52%) | 0.031 |
RACE, n (%) | |||||
Asian | 1 (0.73%) | 0 (0%) | 0 (0%) | 1 (2%) | Â |
Black or African American | 24 (17.52%) | 8 (22.86%) | 7 (13.46%) | 9 (18%) | Â |
Native Hawaiian or other Pacific Islander | 2 (1.46%) | 0 (0%) | 0 (0%) | 2 (4%) | Â |
Not Reported | 3 (2.19%) | 1 (2.86%) | 1 (1.92%) | 1 (2%) | Â |
Unknown | 10 (7.3%) | 4 (11.43%) | 2 (3.85%) | 4 (8%) | Â |
White | 97 (70.8%) | 22 (62.86%) | 42 (80.77%) | 33 (66%) | 0.528 |
ETHNICITY, n (%) | |||||
Hispanic or Latino | 12 (8.76%) | 4 (11.43%) | 3 (5.77%) | 5 (10%) | Â |
Not Hispanic or Latino | 114 (83.21%) | 27 (77.14%) | 44 (84.62%) | 43 (86%) | Â |
Unknown | 11 (8.03%) | 4 (11.43%) | 5 (9.62%) | 2 (4%) | 0.554 |
INSS_STAGE, n (%) | |||||
Stage 2b | 1 (0.73%) | 1 (2.86%) | 0 (0%) | 0 (0%) | Â |
Stage 3 | 5 (3.65%) | 3 (8.57%) | 1 (1.92%) | 1 (2%) | Â |
Stage 4 | 111 (81.02%) | 20 (57.14%) | 43 (82.69%) | 48 (96%) | Â |
Stage 4 s | 20 (14.6%) | 11 (31.43%) | 8 (15.38%) | 1 (2%) | <0.001 |
TUMOR_SAMPLE_HISTOLOGY, n (%) | |||||
Favorable | 25 (18.25%) | 12 (34.29%) | 10 (19.23%) | 3 (6%) | Â |
Unfavorable | 102 (74.45%) | 21 (60%) | 36 (69.23%) | 45 (90%) | Â |
Unknown | 10 (7.3%) | 2 (5.71%) | 6 (11.54%) | 2 (4%) | 0.005 |
DIAGNOSIS, n (%) | |||||
Ganglioneuroblastoma, intermixed | 1 (0.73%) | 0 (0%) | 1 (1.92%) | 0 (0%) | Â |
Ganglioneuroblastoma, nodular | 22 (16.06%) | 5 (14.29%) | 10 (19.23%) | 7 (14%) | Â |
Neuroblastoma | 109 (79.56%) | 27 (77.14%) | 40 (76.92%) | 42 (84%) | Â |
Unknown | 5 (3.65%) | 3 (8.57%) | 1 (1.92%) | 1 (2%) | 0.567 |
RISK_GROUP, n (%) | |||||
High Risk | 113 (82.48%) | 20 (57.14%) | 44 (84.62%) | 49 (98%) | Â |
Intermediate Risk | 10 (7.3%) | 8 (22.86%) | 1 (1.92%) | 1 (2%) | Â |
Low Risk | 14 (10.22%) | 7 (20%) | 7 (13.46%) | 0 (0%) | <0.001 |
OS_STATUS, n (%) | |||||
0:LIVING | 64 (46.72%) | 21 (60%) | 27 (51.92%) | 16 (32%) | Â |
1:DECEASED | 73 (53.28%) | 14 (40%) | 25 (48.08%) | 34 (68%) | 0.024 |
OS_DAYS | |||||
Mean+/−sd | 1622.13+/−1094.61 | 1826.94+/−1162.02 | 1727.88+/−1176.46 | 1368.78+/−916.92 |  |
Median (IQR) | 1544 (723, 2325) | 2064 (806,2500) | 1543.5 (805.75,2267.5) | 1323.5 (487.25,2012.75) | 0.106 |
OS_MONTHS | |||||
Mean+/−sd | 53.81+/−35.97 | 60.46+/−38.14 | 57.29+/−38.68 | 45.54+/−30.19 |  |
Median (IQR) | 51 (24, 77) | 68 (27,82.5) | 51 (26.75,75.25) | 44 (16.75,67) | 0.112 |
