Fig. 2: Analysis of IgG subclasses in seropositive patients.
From: Deep dissection of the antiviral immune profile of patients with COVID-19
Analyzing plasma samples from 20 patients with COVID-19 for IgG responses against the four SARS-CoV virus proteins S1, RBD, S2, and N in an ELISA we found that these responses primarily consisted of the a IgG1 and c IgG3 but not the b IgG2 and d IgG4 subtypes. Full-length GST protein was used as a negative control and Flu and TT proteins served as positive controls. Boxplots extend from the 25th to 75th percentiles, the line indicates the median, and whiskers indicate the range.
