Fig. 7: Detailed characterization of the B cell epitope landscape in COVID-19 patients.
From: Deep dissection of the antiviral immune profile of patients with COVID-19
a Plasma samples from two patients with known SARS-CoV reactivity were analyzed for IgG responses against individual 20mer peptides of the S1 protein covering the RBD (highlighted in yellow), the RBM within the RBD (highlighted in orange), and the region C-terminally adjacent to the RBD. b Plasma samples from six patients with known SARS-CoV reactivity were analyzed for IgG and IgA responses against individual 20mer peptides of the N protein. Values represent ODs in an ELISA assay and shared epitopes are marked using dotted lines.
