Fig. 2: Plasma metabolite levels measured during and after spaceflight.
From: Nrf2 plays a critical role in the metabolic response during and after spaceflight
a, b Metabolic changes in plasma collected from the tails of WT (a) and Nrf2 KO (b) mice (dataset M241). Fold changes in plasma metabolite levels at L+18 (blue dots) compared to L-17 and R+2 (yellow dots) compared to L-17. c, d CV values of dataset M241 in the plasma of WT (c) and Nrf2 KO (d) mice at three time points: WT L-17 (cyan), L+18 (blue) and R+2 (yellow) and Nrf2 KO L-17 (cyan), L+18 (blue) and R+2 (yellow). Data are presented as the CV (%) of the metabolite concentrations. The horizontal axis indicates M241 metabolite IDs (Supplementary Data 2) and includes 20 amino acids (#3–22), 23 amino acid-related metabolites (#23–45), 6 cholesteryl esters (#83–88), 9 lysophosphatidylcholines (#90–98), 63 phosphatidylcholines (#99–161), 11 sphingolipids (#162–172) and 69 triacylglycerols (#173–241).
