Table 1 Rate and affinity constants for galectin-1 binding.

From: Chemokines modulate glycan binding and the immunoregulatory activity of galectins

Analyte

ka(Ms-1)

kd1 (s-1)

kd2 (s-1)

K1

K2

Anginex

6.5 × 103 (±1.7)

4.2 × 10−2 (±0.4)

5.9 × 10−4 (±1.9)

6.4 ± 1.7 μM

90.0 ± 6.7 nM

CXCL4

1.02 × 104 (±0.05)

9.2 × 10−2 (±1.2)

5.0 × 10−3 (±0.5)

9.0 ± 0.8 μM

483 ± 28 nM

BSA

–

–

–

–

–

  1. The association rate constant (ka) was obtained by plotting the kobs as a function of analyte concentration. K1 is defined as kd1/ka and K2 is defined as kd2/ka. BSA bovine serum albumin. – No interaction detected.
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