Fig. 1: Normalized copy number of EIF2S3Y in eleven tissues from young and old rats. | Communications Biology

Fig. 1: Normalized copy number of EIF2S3Y in eleven tissues from young and old rats.

From: Rats exhibit age-related mosaic loss of chromosome Y

Fig. 1

a Coverage of EIF2S3Y normalized by the coverage of the autosomal gene COL1A1 in nine tissues of three months old rats (data from blood and skin were inadvertently lost; see Methods). b Coverage of EIF2S3Y normalized by the coverage of the autosomal gene COL1A1 in eleven tissues of 22–25 months old rats. a, b bl is blood, br is brain, ht is heart, kd is kidney, lv is liver, lg is lung, ms is muscle, pa is pancreas, sk is skin, sp is spleen, ts is testis. Significant differences, Mann–Whitney U test against a distribution with a fixed median of 0 (no difference against expected estimates). P values were Benjamin–Hochberg corrected: * indicates P < 0.05; *** indicates P < 0.001. Sample sizes are indicated in parenthesis. Error bars, maximum and minimum values, excluding outliers.

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