Fig. 2: Circular RNA expression in glioma. | Communications Biology

Fig. 2: Circular RNA expression in glioma.

From: Genome-wide perturbations of Alu expression and Alu-associated post-transcriptional regulations distinguish oligodendroglioma from other gliomas

Fig. 2

a Differences of Alu association with gene bodies between the two gene groups with and without circular RNA-supporting RNA-seq reads (back-splicing junction reads). b The number of circular RNA-supporting reads per one million reads in RNA-seq. The numbers were plotted for individual patients (dots) and tumor and normal tissues (y and x axis values respectively) according to different pathologies (colors): grade 2 oligodendroglioma IDH mutant and 1p/19q-codeleted (O2), grade 3 oligodendroglioma IDH mutant and 1p/19q-codeleted (O3), grade 2 IDH mutant astrocytoma (A2), grade 3 IDH mutant astrocytoma (A3), and glioblastoma (GBM). c Distributions of circular RNA expression rate changes in tumors relative to matched normal tissues were described in a cumulative way for different pathologies: the shift of the curve to the left to 0 means overall decrease in tumor relative to normal tissues.

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