Fig. 3: Alu RNA expression in glioma. | Communications Biology

Fig. 3: Alu RNA expression in glioma.

From: Genome-wide perturbations of Alu expression and Alu-associated post-transcriptional regulations distinguish oligodendroglioma from other gliomas

Fig. 3

a The numbers of significantly-perturbed Alu RNAs among total 47 Alu subfamilies annotated in GENCODE (v27) for different pathologies. b Volcano plots of differential gene expression analyses per brain tumor pathologies. Alu elements (red), non-Alu transposable elements (blue) and the annotated genes (gray) were described according to the results of differential gene expression analysis. X-axis is fold change of RNA levels in log2 scale (tumor relative to normal) and y-axis is p value in the negative log scale (base:10). c Distribution of Alu RNA expression changes in tumors relative to matched normal tissues were described in a cumulative way for different pathologies. Label of pathologies: grade 2 oligodendroglioma (O2), grade 3 oligodendroglioma (O3), grade 2 astrocytoma (A2), grade 3 astrocytoma (A3), grade 4 astrocytoma (A4), and glioblastoma (GBM).

Back to article page