Table 1 Top 20 features used in the boosted trees of the AD-focused MPXgb model.
Feature | Data source | Gain |
|---|---|---|
PPI:GAPDH | STRING | 0.27852 |
PPI:IL10 | STRING | 0.08283 |
PPI:GSTP1 | STRING | 0.03823 |
Darunavir:HELA signature | LINCS | 0.03732 |
Aminosalicylic acid:MCF7 signature | LINCS | 0.03413 |
Blonanserin:PC3 signature | LINCS | 0.03004 |
Amiloride:MC7 signature | LINCS | 0.02594 |
Trifluridine:PC3 signature | LINCS | 0.02048 |
Brain - Anterior cingulate cortex (BA24) | GTEx | 0.01866 |
Travoprost:HA1E signature | LINCS | 0.01848 |
Regulation of mRNA stability by proteins that bind AU-rich elements | Reactome | 0.01775 |
PPI:JAK2 | STRING | 0.01729 |
PPI:BDNF | STRING | 0.01684 |
PPI:IL2 | STRING | 0.01593 |
Levosulpiride:PC3 signature | LINCS | 0.01556 |
Azelaic acid:MC7 signature | LINCS | 0.01538 |
Saquinavir:A549 signature | LINCS | 0.01534 |
Cyproterone:MC7 signature | LINCS | 0.01411 |
Vorinostat:HT115 signature | LINCS | 0.01138 |
Trifluoperazine:WSUDLCL2 signature | LINCS | 0.01092 |
