Fig. 1: Serum and intestinal IGF-1 are developmentally regulated during the perinatal period in mice. | Communications Biology

Fig. 1: Serum and intestinal IGF-1 are developmentally regulated during the perinatal period in mice.

From: Macrophage-derived IGF-1 protects the neonatal intestine against necrotizing enterocolitis by promoting microvascular development

Fig. 1

Pups from each litter were randomly assigned to different time-points. Serum and intestinal tissues were collected from mice at embryonic day 17.5 (E17.5), day of life 0, 1, 2, 3, 7, 14, and 21. a IGF-1 serum level was measured by ELISA, n = 4–12/time point (exact n at each time point see dots in the panels and Source Data file.), data represent results of three experiments combined (mean ± SEM). b Intestinal IGF-1 and IGF-1R were examined by western blot analysis. Data represent the results of three experiments. n = 2/time point for every three separate experiments (mean ± SEM). One of the three experiments did not include E17.5 time point. Gel images are included in Source Data file.

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