Fig. 2: Molecular determinants of Adc stack formation.

a Atomic model of a 2-decamer stack shown as cartoons, with domains coloured as in Fig. 1a. The inset shows a closeup of the decamer:decamer interface in the stack, with the key stack-forming residues D472 and R492 shown as sticks. b Multiple sequence alignment of Adc sequences from E. coli (WP_001381593.1), Salmonella Typhimurium (WP_000978690.1), P. stuartii (WP_004923888.1) and P. rettgeri (WP_164564359.1) focused on region around key stack-forming residues D472 and R492 in the P. stuartii Adc (indicated by boxes), coloured according to the AliView colour scheme.