Fig. 4: RNA-sequencing reveals the metabolic signature in ROCK2-null podocytes.
From: ROCK2-induced metabolic rewiring in diabetic podocytopathy
a The experimental approach to generate samples for high throughput RNA-sequencing. Murine podocytes were treated with negative control (siCtrl) or siRNA against ROCK2 (siR2). b, c A heat map (b) and volcano plot (c) of differentially expressed genes in podocytes based on log (fold change) >1.5 with adjusted p < 0.05. d Results of a gene-set enrichment analysis (p value top 20).
