Fig. 4: STK25 controls ER stress in human aortic endothelial and smooth muscle cells. | Communications Biology

Fig. 4: STK25 controls ER stress in human aortic endothelial and smooth muscle cells.

From: Silencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is atheroprotective

Fig. 4

hASMCs and hAECs were transfected with STK25 siRNA or NTC siRNA. a, b Representative images of cells processed for immunofluorescence with anti-KDEL (red) or anti-CHOP (green) antibodies; nuclei stained with DAPI (blue). Quantification of the staining. c Relative gene expression of selected ER stress markers. In (a, b), the scale bars represent 100. Data are mean ± SEM from 5 to 6 wells per group. OA, oleic acid. *P < 0.05, **P < 0.01, ***P < 0.001 for STK25 siRNA vs. NTC siRNA.

Back to article page