Fig. 3: Deletion of NEMO in PSCs promotes tissue and peripheral eosinophilia. | Communications Biology

Fig. 3: Deletion of NEMO in PSCs promotes tissue and peripheral eosinophilia.

From: Functional IKK/NF-κB signaling in pancreatic stellate cells is essential to prevent autoimmune pancreatitis

Fig. 3

a Expression of chemokines and chemokine receptors in pancreata analyzed by qPCR (n = 8). b Percentage of Siglec-F+/CD45+ cells analyzed by FACS (n = 3). c FACS analysis illustrating the eosinophil population (gate on CD45+CD11b+CD11c−Ly6G−CCR3+SiglecF+ cells) in pancreas and circulation. d Expression of eosinophil markers (Siglecf and Prg2) detected in the pancreata by qPCR (n = 8). e Staining of Siglec-F on pancreatic tissues. DAPI: nuclei. Scale bar: 50 µm. Whiskers: Min to Max. T-test (two-tailed): *p < 0.05; **p < 0.01; ****p < 0.0001. All n numbers represent biological replicates.

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