Fig. 1: Overview of Methodology. | Communications Biology

Fig. 1: Overview of Methodology.

From: Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome

Fig. 1

Principal steps of investigation: Following blinded preprocessing, artifact-free EEG data and a cortical lead field matrix were used to construct a weighted minimum norm estimate (MNE) source model to estimate current source density and spectral power by frequency band at each vertex of a triangular cortical mesh. Based on hypotheses, subsequent analyses were performed at four different levels: raw vertices, parcellation of vertex points into Desikan–Killiany atlas-based nodes, cortical regions (contiguous anatomical grouping of nodes), and/or resting-state networks (RSN) (functional non-continuous grouping of nodes).

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