Fig. 6: Tecrl regulates PI3K/Akt signaling and mitochondrial fusion protein in hiPSC-CMs.
From: TECRL deficiency results in aberrant mitochondrial function in cardiomyocytes
a Representative immunofluorescence images of OCT4 in the hiPSCs (n = 3). b Representative immunofluorescence images of α-actinin and cTnT in the hiPSC-CMs (n = 6). c Representative images and quantification of the velocity of contraction and relaxation of hiPSC-CMs. d–g Representative immunoblotting images and quantification of the expression of p-AKT, NRF2, MFN2, FAS, and TECRL in hiPSC-CMs following TECRL knockdown. Values are mean ± SE. P < 0.05 was considered significant.
