Fig. 3: A single mutation G178W replaces and mimics the carotenoid binding. | Communications Biology

Fig. 3: A single mutation G178W replaces and mimics the carotenoid binding.

From: Carotenoid binding in Gloeobacteria rhodopsin provides insights into divergent evolution of xanthorhodopsin types

Fig. 3

a Comparison of proton pumping of GR wild-type, G187W mutant, and GR-carotenoid. b Retinal bleaching from opsin when exposed to high pH condition, G178W showed pH tolerance over GR-bound carotenoid and wilt-type. c Local view of G178W mutant and the polar interactive change of surrounding residues, while replacement of Gly to Trp make the overlap ring to the carotenoid 4-keto ring of carotenoid.

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