Fig. 3: Distribution of ARGs and MGEs in GWI Veteran groups.
From: Host gut resistome in Gulf War chronic multisymptom illness correlates with persistent inflammation
a Box plot showing relative abundance (%) of ARGs in Hum_Control (Veteran group without GWI symptom, n = 5 biologically independent samples) and Hum_GWI (Veteran group with GWI symptom, n = 28 biologically independent samples). Median values of 9.0% in Hum_Control and 9.86% in Hum_GWI are indicated by solid black lines. b Procrustes rotation analysis comparing resistome (blue) and microbiome (red) changes using PCA ordinations, (X-axis: PCA1, Y-axis: PCA2, PROTEST, M2 = 0.6665, p = 0.0001). c PCoA of Bray-Curtis dissimilarity between ARGs and Taxa. Principal coordinate axes PCoA1(12.7%) and PCoA2 (11.5%) account for 24.2% of detected variance. d Box plot showing relative abundance (%) of selected MGEs in Hum_Control and Hum_GWI. Boxes in the box plots indicate interquartile range. Error bars in the box plots extend to the most extreme values within 1.5 times the interquartile range. Outlier data points are represented by black dots drawn outside of the box plot. p-values were determined using PROTEST or Welch’s t-test where p < 0.05 was considered statistically significant.
