Fig. 2: Identification of beige adipocytes within mature adipocytes.
From: Remodeling of gene regulatory networks underlying thermogenic stimuli-induced adipose beiging
a UMAP plot of normalized Pparg gene accessibility. b UMAP plot of normalized PPARG motif enrichment. c UMAP plot of white and beige adipocytes among mature adipocytes (n = 7,004). d Heatmap of the relative cell abundance in white and beige adipocyte clusters for each group. e Normalized accessibilities of adipogenic or common adipocyte genes and thermogenic or beige-selective genes. f Differentially accessible genes between white and beige adipocytes. Positive and negative log2-fold changes respectively indicate increased accessibility in white and beige adipocytes. Genes with adjusted p-value < 10−100 & Abs(log2 fold-change) > 0.25 are colored and labeled. g, h GO g and KEGG pathway h analysis of genes enriched in beige adipocytes compared to white adipocytes. X-axis indicates number of genes. Color indicates adjusted p-value.
