Fig. 5: ML induced mitophagy via upregulating the nuclear translocation of TFEB in HUVECs. | Communications Biology

Fig. 5: ML induced mitophagy via upregulating the nuclear translocation of TFEB in HUVECs.

From: Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival

Fig. 5

a, b The expression of cytoplasmic and nuclear TFEB in HUVECs in control, TBHP and TBHP + ML groups. c, d Subcellular localization of TFEB measured immunofluorescence in control, TBHP and TBHP + ML groups (bar: 20 μm). e, f The protein expression of whole TFEB and in HUVECs was detected by western blot. g, h Western blots were used to measure the expression of protein P62, LC3, C-caspase3 and SOD1. All experiments have been performed at least 3 times. Data are presented as mean ± S.D. n = 3, **P < 0.01, *P < 0.05.

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