Fig. 7: Arterial-stiffness precedes cardiac disease and peripheral blood pressure alterations. | Communications Biology

Fig. 7: Arterial-stiffness precedes cardiac disease and peripheral blood pressure alterations.

From: Progressive aortic stiffness in aging C57Bl/6 mice displays altered contractile behaviour and extracellular matrix changes

Fig. 7

Echocardiograms were used to assess interventricular septum (IVS) thickness (a) and left ventricular internal diameter (LVID, b). Cardiomyocyte cross-sectional area was studied using immunohistochemical staining for laminin (c). Peripheral systolic blood pressure (SBP, d), diastolic blood pressure (DBP, e) and pulse pressure (PP, f) were measured. Each symbol represents an individual biological repeat (n > 8). Statistical analysis using one-way ANOVA. Overall significance (bottom of graph) and post hoc significance vs. 4-month value (in graph) are listed. ***p < 0.001.

Back to article page