Fig. 9: Illustration of the deletion of EPSs and O-antigen made H. bluephagenesis self-flocculating and electrotransformation feasible.

a EPSs and O-antigen synthesis gene clusters of H. bluephagenesis TD1.0 were deleted with dual-sgRNA CRISPR/Cas strategy, and resulted in H. bluephagenesis ΔPS124. b H. bluephagenesis ΔPS124 can self-flocculate in the range of 0.4–1.0 M NaCl concentration, while H. bluephagenesis ΔPS124 cannot. c H. bluephagenesis ΔPS124 can be transformed by electroporation, whereas H. bluephagenesis ΔPS124 cannot.