Fig. 1: Nematicidal Bt infection leads to energy imbalance in C. elegans.

a An Enrichment Pathway analysis of RNA-Seq data using KOBAS showing the top 20 pathways influenced by nematicidal Bt infection. b Analysis of the AMP/ATP ratio by LC/MS. The wild-type N2 and bre-5(ye17) worms were fed with OP50, BMB171/pHT304, and BMB171/Cry5Ba for 4 h. N = 3 independent experiments. Data points represent the mean values of three independent replicates, error bars denote the SD. The p-value was determined by a Student’s t-test (Welch’s correction for unequal variances), ***p < 0.001.