Fig. 2: Midbrain and non-midbrain DRT correlate with cognitive control network in standard feedback group.

To investigate whole-brain neural activity correlating with successful SN/VTA self-regulation, we used midbrain DRT as measure of successful regulation of the SN/VTA and correlated it with non-midbrain DRT (DRT: IMAGINE_REWARDtransfer - RESTtransfer) – (IMAGINE_REWARDbaseline – RESTbaseline). a The analysis revealed correlations primarily within the cognitive control network (whole-brain overview FWE-corrected with p < 0.05 at cluster level, projected to lateral and medial sagittal sections). b Exemplary correlations within the cognitive control network in MFG/dlPFC, ACC, thalamus, and bilateral temporal gyrus, illustrating the association between midbrain DRT and non-midbrain DRT. The correlations are for illustration purposes only without further significance testing to avoid double dipping. The grey shaded area identifies the 95% confidence interval. See Table 1 for full result overview (n = 42 subjects).