Fig. 7: An overview of the neurofeedback paradigm.

a All runs consisted of alternating blocks of REST and IMAGINE_REWARD conditions, with each block lasting 20 s. The regulation conditions (REST, IMAGINE_REWARD) were indicated by words (‘Rest’ or ‘Happy Time!’) and the feedback presented as moving smiley face during neurofeedback training runs. The baseline and transfer runs comprised no feedback. The SN/VTA signal difference from these runs served to quantify the degree of regulation transfer (DRT) as (SN/VTA_BOLD{IMAGINE_REWARD,Transfer} – SN/VTA_BOLD{REST,Transfer}) – (SN/VTA_BOLD{IMAGINE_REWARD,Baseline} – SN/VTA_BOLD{REST,Baseline}). b Post-processed SN/VTA signal was extracted from the probabilistic atlas mask98. c The analysis scheme highlights partial data of the paradigm used to investigate the three aims of this study.