Fig. 5: HLA-I expression and response to DNMT and HDAC inhibition ex vivo. | Communications Biology

Fig. 5: HLA-I expression and response to DNMT and HDAC inhibition ex vivo.

From: Reversible epigenetic alterations regulate class I HLA loss in prostate cancer

Fig. 5

a Gene expression analysis of the HLA-I genes and prostate-specific elements of the AR pathway in prostate tumor tissue cultured ex vivo. b Gene expression analysis of induction of HLA-I and AR pathway elements in ex vivo tissue treated with DMSO, 5AZA2, LBH, or 5AZA2 + LBH; n = 3. Error bars represent SD.

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