Fig. 3: AdSpike has little effect on calcium handling properties of cultured cardiomyocytes subjecting to electrical field stimulation with or without hyp-reox injury.

Averaged parameters of calcium transient of hCMs (a) or neonatal rat cardiomyocytes (nrCM, b) infected by AdVector or AdSpike with different frequency of electrical field stimulation. n = 15–30 for each group. Statistical significance was assessed using 2-way ANOVA with Turkey post-test. Data are presented as mean ± SEM; n.s., not significant as compared with the corresponding AdVector control, in which the black color indicates comparison within the normoxia group, and gray color indicates comparison within the hyp-reox group.