Fig. 5: Comparison of cocaine’s effects on neuronal fluorescence \(\Delta {F/F}_{{{{\rm{Ca}}}^{2+}}{\mbox{-}{{{\rm{G(N)}}}}}}\), tissue Δ[HbO2], and Δ[HbT] in arteries.
From: Cocaine’s cerebrovascular vasoconstriction is associated with astrocytic Ca2+ increase in mice
a Mean \(\Delta {F/F}_{{{{\rm{Ca}}}^{2+}}{\mbox{-}{{{\rm{G(N)}}}}}}\) (green), Δ[HbO2]-G(N) (orange), and Δ[HbT]-G(N) (red) changes with time in cortex in response to cocaine (1 mg/kg, i.v.) (n = 5). b Correlation between cocaine-induced response in \(\Delta {F/F}_{{{{\rm{Ca}}}^{2+}}{\mbox{-}{{{\rm{G(N)}}}}}}\) and Δ[HbO2]-G(N) showed a strong inverse linear association (R = −0.984, p < 0.01). All error bars are presented as means ± SEM.
