Fig. 9: Effects of DHA injection and colistin combination therapy against E. coli W3110 (pUC19-mcr-1) in vivo. | Communications Biology

Fig. 9: Effects of DHA injection and colistin combination therapy against E. coli W3110 (pUC19-mcr-1) in vivo.

From: Commercialized artemisinin derivatives combined with colistin protect against critical Gram-negative bacterial infection

Fig. 9

a Mouse infection model monitoring including survival rate, time of treatment, Wt. Loss (weight loss), morbidity score, bacterial loading and histopathological observation. b Survival plot of mice inoculated via intraperitoneal injection with E. coli W3110 (pUC19-mcr-1) (17 mice per group). c–h The Wt. Loss (c), morbidity score (d), histopathological observation (e) and the bacterial burden in the blood (f), liver (g) and spleen (h) were calculated (n = 10). **P < 0.01. ns indicates no significant.

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