Fig. 3: Cell clusters of nonimmune cells and transcriptomic difference of glial cells between TDL and glioma. | Communications Biology

Fig. 3: Cell clusters of nonimmune cells and transcriptomic difference of glial cells between TDL and glioma.

From: Integrative and comparative single-cell analysis reveals transcriptomic difference between human tumefactive demyelinating lesion and glioma

Fig. 3

a, b UMAP plots with expression level of SOX2 and PTPRZ1 revealed the two benign clusters (C5, C17) derived from both glioma and TDL. c Proportion plot of nonimmune clusters deriving from TDL and glioma. d Volcano plot of differentially expressed genes (DEGs) that are upregulated (red) or downregulated (blue) in glial cells (C5) of TDL by comparing to glial cells (C5) of glioma. e Treemap of Gene Ontology (GO) enrichment analysis for biological process based on DEGs between C5 cells from TDL and glioma. TDL tumefactive demyelinating lesion, UMAP Uniform Manifold Approximation and Projection. DEGs differentially expressed genes, FC fold change.

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