Fig. 2: Volcano plot of DESeq2 calculated differential expression results from RNA sequencing.

Log2-fold-changes comparing BALB/cN to C57BL/6 N expression (x-axis) plotted against -log(10) of the recalibrated p-value after adjustment for multiple testing (y-axis). Significantly differentially expressed genes with adjusted p < = 0.05 (dotted line) colored blue, non-significant differences in black, differentially expressed genes overlapping chr17 locus after filtering for relevant transcript types colored red, with Cbs as the most strongly downregulated gene after filtering.