Fig. 1: Successive coronal MRI images in MNI stereotaxic coordinates (Y) depicting the lesion of patient AA. | Communications Biology

Fig. 1: Successive coronal MRI images in MNI stereotaxic coordinates (Y) depicting the lesion of patient AA.

From: Specific disruption of the ventral anterior temporo-frontal network reveals key implications for language comprehension and cognition

Fig. 1

The lesion appears at Y35 and continues as far as Y20, including a part of the pars triangularis (area 45) and the white matter below (see Y26, Y21). At Y19, the lesion also includes part of the caudate, the adjacent internal capsule (IC), the external capsule (EC), and the temporo-frontal extreme capsule fasciculus (TFexcF), just below insular gyrus Brevis I (GBI). Subcortically, there is damage to the claustrum, putamen, and the anterior part of the insula (GBI) under which courses the TFexcF. From Y15 to Y7, the lesion includes a small part of the anterior STG. Moving on posteriorly, between Y3 and Y-3, one can observe damage to the TFexcF which courses between the claustrum and the anterior insula (gyrus Brevis III; GBIII), the STG and a small part of MTG, including both banks of the superior temporal sulcus (sts) (see Y0). At Y-7, one observes that the lesion is located anterior to the level of the sulcus acousticus (sa) that lies on the lateral STG (see also Fig. 2). Subcortically, the lesion includes part of the caudate, IC, EC, TFexcF between the claustrum and insular gyrus Brevis III and gyrus Longus I & II, STG, sts and the whole MTG. The temporal lesion is visible as far posterior as Y-15 where it is restricted to the insula, caudate, putamen, claustrum, EC, TFexcF, and at Y-19 to putamen and lower insula, leaving Heschl’s gyrus and the surrounding temporal areas completely spared. Posterior to Y-20, no lesion is detected. Brain areas are topologically defined according to the atlas of the morphology of the human cerebral cortex in the MNI Stereotaxic Space67. aalf ascending anterior ramus of the lateral fissure; GBI gyrus brevis I of insula; GBIII gyrus brevis III of insula; GLI gyrus longus I of insula; GLII gyrus longus II of insula; half horizontal ascending ramus of the lateral fissure; HG Heschl’s gyrus; IFG:Tr inferior frontal gyrus, pars triangularis; IFG:Op inferior frontal gyrus, pars opercularis, Or pars orbitalis; Tr pars triangularis; ifs inferior frontal sulcus; lf lateral fissure; MFG middle frontal gyrus; MTG middle temporal gyrus; PoG postcentral gyrus; PrG precentral gyrus; sts superior temporal sulcus; ts triangular sulcus.

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