Fig. 4: Lateral view of the left hemisphere lesion of patient MM with damage to the dorsal posterior language region.

The area affected by the lesion is marked with the blue color. The lesion includes the posterior temporal region, i.e. clearly posterior to the level of the sulcus acousticus (sa). It also includes the Heschl’s gyrus (HG) region, which lies within the lateral fissure, and a part of the posterior middle temporal gyrus (pMTG). Thus, the posterior temporal region (Wernicke’s area) is damaged. The lesion extends to the supramarginal (SMG) and angular (ANG) gyri of the inferior parietal lobule. Thus, the lesion is restricted to the dorsal posterior language network, sparing all cortical areas associated with the ventral language network, i.e. the anterior to intermediate temporal areas and their connections via the TFexcF to area 45 on the IFG. The lesion was reconstructed in MNI stereotaxic space and projected on the standard average MNI brain65,66. Abbreviations: ANG angular gyrus; csts1 caudal superior temporal sulcus, first segment; csts2 caudal superior temporal sulcus, second segment (angular sulcus); csts3 caudal superior temporal sulcus, third segment (anterior occipital sulcus); ipcs inferior postcentral sulcus; ips intraparietal sulcus; lf lateral fissure; pMTG posterior middle temporal gyrus; pSTG posterior superior temporal gyrus; sa sulcus acousticus; SMG supramarginal gyrus; sts superior temporal sulcus.