Fig. 5: Successive coronal MRI images in MNI stereotaxic coordinates (Y) depicting the lesion of patient TA with damage to the dorsal posterior language region. | Communications Biology

Fig. 5: Successive coronal MRI images in MNI stereotaxic coordinates (Y) depicting the lesion of patient TA with damage to the dorsal posterior language region.

From: Specific disruption of the ventral anterior temporo-frontal network reveals key implications for language comprehension and cognition

Fig. 5

The lesion starts posterior to the central sulcus (cs) and after Y-24. At Y-27, the white matter below SMG and postcentral gyrus areas 2, 1, 3b is damaged affecting SLF III fibers (originating from the SMG), SLF II fibers (originating from ANG), and AF fibers (originating from Tpt. At Y 31, a small area of anterior SMG is added to the white matter lesion. At Y-35 and Y-39, the lesion includes SMG and the white matter below. At Y-43, the whole SMG, the white matter below and a small part of area Tpt, that is the caudal STG, is damaged, leaving primary acoustic areas on Heschl’s gyrus intact. Further posteriorly, at Y-47, -51, -55 as well as -59, damage continues to include the whole SMG and SPL (Superior Parietal Lobe), occupying a larger part of STG (see Y-55). At Y-63, superior and inferior parietal lobule areas, including areas PFm and PG, as well as the white matter below, until csts3 are affected. At Y-67 till Y-71, the superior and inferior parietal lobule areas, including ANG, as well as the underlying white matter until the area just below csts2, are lesioned (see Y-69). At Y-75, Y-79, and Y-83, the precuneus, superior and inferior parietal lobule areas until csts3 are affected, while at Y-83, the lesion includes the areas of POA and the whole ANG until csts3. The lesion continues further posteriorly to parieto-occipital areas, affecting even occipital areas such as area 19, in Y-98, where the lesion ends. Brain areas are topologically defined according to the atlas of the morphology of the human cerebral cortex in the MNI Stereotaxic Space67. 3a: area 3a; 37o: lateral occipitoparietal area 37; AF Arcuate Fasciculus; ANG angular gyrus; cs central sulcus; csts1, csts3 caudal superior temporal sulcus, 1st and 3rd ramus; IPL inferior parietal lobule; ipcs inferior postcentral sulcus; ips intraparietal sulcus; ips-po intraparietal sulcus, paroccipital part; lf lateral fissure; MTG middle temporal gyrus; POA parieto-occipital arcus; PoG postcentral gyrus; PrCu precuneus; SLFII/III superior longitudinal fasciculus, subdivision II/III; SMG supramarginal gyrus; SPL superior parietal lobule; STG superior temporal gyrus; sts superior temporal sulcus; Tpt caudal superior temporal cortical region.

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