Table 2 Drugs changed the thermal stability of Mtb EF-Tu.
Name | Target | Pathway | Tm (°C) |
|---|---|---|---|
Doxazosin | Adrenergic receptor | Neuronal signaling | 47 |
Fenoterol hydrobromide | Adrenergic receptor | Neuronal signaling | 45.4 |
Metoprolol tartrate | Adrenergic receptor | Neuronal signaling | 59.5 |
Domperidone | Dopamine receptor | Neuronal signaling | 45.8 |
Alvimopan | Opioid receptor | Neuronal signaling | 56.9 |
Motolimod | TLR | Immunology | 48 |
Montelukast | LTR | Immunology | 43.2 |
Estriol | Estrogen receptor | Endocrinology | 44 |
Aliskiren temifumarate | RAAS | Endocrinology | 46.8 |
Canagliflozin hemihydrate | SGLT | GPCR & G protein | 44.1 |
Lixisenatide | Glucagon receptor | GPCR & G protein | 55.4 |
Osimertinib (AZD9291) | EGFR | Protein tyrosine kinase | 60.2 |
Saracatinib (AZD0530) | Src | Angiogenesis | 61.1 |
Carvedilol Phosphate | Others | Others | 75.9 |
Thioridazine hydrochloride | Others | Others | 58 |
Aliskiren | Others | Others | 46.7 |
