Fig. 6: ADSS deficiency provokes more dramatic GMP cell expansion induced by IMP. | Communications Biology

Fig. 6: ADSS deficiency provokes more dramatic GMP cell expansion induced by IMP.

From: The purine metabolite inosine monophosphate accelerates myelopoiesis and acute pancreatitis progression

Fig. 6

a glucose tolerance, n = 10. b Plasma levels of cholesterol and triglyceride. c, d ADSS expression levels in BMC expressed in liver and BMC. n = 9–10. e, f Frequency and absolute number of GMP cells in WT and ADSS+/− mice. n = 10. g, h ATP and GTP levels in lineage−/low cells after three days of IMP treatment. n = 5. i Yielded GMP cells after three days of IMP stimulation in vitro. n = 8. Unpaired, 2-tailed Student’s t test for data with normal distribution. Non-parametric Mann–Whitney analysis was used for the data did not follow normal distribution.

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