Fig. 4: detection of distinct clinical groups via PCA and clustering. | Communications Biology

Fig. 4: detection of distinct clinical groups via PCA and clustering.

From: An explainable model of host genetic interactions linked to COVID-19 severity

Fig. 4

a Projection of samples (n = 841) along the 1st and 2nd principal components and coloring based on severity (up) or clusters identified via k-means (bottom); b gender and clinical group composition of the clusters detected via k-means on the 1st and 2nd PCA components; c FI network constructed using mutated genes on the cluster of more severe patients and approved drugs available for any of these genes.

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