Fig. 6: Fluconazole displays a strong predicted affinity for the glucose binding site of CgHxt4/6/7. | Communications Biology

Fig. 6: Fluconazole displays a strong predicted affinity for the glucose binding site of CgHxt4/6/7.

From: Genomic evolution towards azole resistance in Candida glabrata clinical isolates unveils the importance of CgHxt4/6/7 in azole accumulation

Fig. 6

a Overlap of the best DOPE score model and the template E. coli XylE (PDB ID 4GBZ) (pink). Loop regions that differ from the template are represented in green. b Docking of fluconazole on the modelled CgHxt4/6/7 structure, best pose. c Docking of D-glucose on the modelled CgHxt4/6/7 structure, best pose. Figures were prepared using PyMOL2.5.

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