Fig. 2: Expression heatmaps of genes that reside in the LD blocks of the eight significant genetic markers. | Communications Biology

Fig. 2: Expression heatmaps of genes that reside in the LD blocks of the eight significant genetic markers.

From: A genome-wide association study with tissue transcriptomics identifies genetic drivers for classic bladder exstrophy

Fig. 2

a Genes expression pattern in mouse embryonic bladder from embryonic day E10.5 to E12.5, E12.5 to E15.5, and E10.5 to E15.5. b Genes expression pattern in human embryonic and fetal bladder from week 7 to 7–7.5, 7–7.5 to 7.5, 7 to 7.5, 7.5 to 8, 8 to 9, and 7 to 9. c Genes expression pattern of 3-year-old control bladder tissue compared to Bladder carcinoma (Bladder Ca), Bladder squamous cell carcinoma (Squamous cell Ca), Bladder transitional cell carcinoma (Transit. cell Ca), Ureter urothelial carcinoma (Ur. Urothelial Ca), Muscle invasive urothelial cancer (Mus. Inv. Urothelial Ca). Legend: Suppressed = gene is silenced and no expression is detected. Activated = gene shows expression after a silenced state.

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