Fig. 3: Total retinal thickness at baseline vs. 12-months as assessed by SD-OCT.
From: Prostaglandin-based rAAV-mediated glaucoma gene therapy in Brown Norway rats
Significant thinning of the retina was observed at various eccentricities from the optic nerve at the 12-month timepoint for both untreated (a–c) and treated eyes (d, f) as compared to baseline measurements. No significant thinning was noted in the medium dose treated eyes (e). (Two-way ANOVA with post hoc Sidak’s multiple comparison test, p = 0.0123-0.0335 (*), 0.0027-0.0087 (**), 0.0007 (***), and <0.0001(****)). Box plot elements: mean = +, centerline = median, box limits = 25th and 75th percentiles, whiskers = min and max).
