Fig. 4: Ear swelling and immune parameters correlated to the metabolite concentrations during acute and chronic cutaneous DTHR. | Communications Biology

Fig. 4: Ear swelling and immune parameters correlated to the metabolite concentrations during acute and chronic cutaneous DTHR.

From: Acute and chronic inflammation alter immunometabolism in a cutaneous delayed-type hypersensitivity reaction (DTHR) mouse model

Fig. 4

Ear swelling thickness, T cell (CD3), macrophage and neutrophil epidermal inflammation scores were correlated to metabolite concentration changes over the whole experimental setup, showing autoscaled (−1; 1) (a) positive (red) and (b) negative (blue) correlation with correlation coefficient statistical significance P values: ****<0.0001, ***<0.001, **<0.01, *<0.05, based on Pearson r distance measure (n = 5 animals).

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