Fig. 2: Association between maternal ppBMI and placental DNAm (N = 2631 placental DNA samples), after adjusting for maternal age, parity, maternal education, maternal smoking and putative cellular heterogeneity.

Association results are displayed as a volcano plot, where the X-axis shows the effect sizes (ranging between 0 and 1) in DNAm and b Manhattan plot, where the X-axis represents the genomic location of each CpG. In both panels blue dots indicate significantly associated CpGs (meta-analysis p-value < 1.2e-07).