Fig. 1: Experimental strategy.

a Cell population-specific mRNA and DNA preparation from D1-BAC-TRAP and D2-BAC-TRAP mice. D1- or D2-specific mRNA was recovered by immunoprecipitation of ribosomes containing EGFP-RPL10A with anti-GFP antibodies. D1- or D2-specific DNA was obtained by FANS using the fluorescence of nucleoli containing EGFP-RPL10A during ribosomal assembly, followed by DNA extraction. b Strand-specificity of the MeDIP-seq and hMeDIP-seq procedures.