Fig. 7: 5hmC asymmetry is associated with gene expression. | Communications Biology

Fig. 7: 5hmC asymmetry is associated with gene expression.

From: DNA methylation and hydroxymethylation characterize the identity of D1 and D2 striatal projection neurons

Fig. 7

a Violin plots of the 5hmC asymmetry ratios in D1 neurons on the template and coding strands of coding genes with different expression levels. b Metagene profiles of 5hmC on the template and coding strands, for the highly expressed genes (top 50% of expressed coding genes). c Enriched gene ontology terms (molecular function, FDR < 2 × 10−2) for genes with the 10% lowest or 10% highest 5hmC ratio of the template strand. e Violin plots of the 5hmC asymmetry ratios on template and coding strands, for olfactory receptors genes and ribosomal proteins. In a and d, horizontal solid lines are medians, and dotted lines are quartiles.

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