Fig. 1: scRNA-seq analysis defined types of fibroblasts and myofibroblasts in human colon mucosa.
From: An integrated map of fibroblastic populations in human colon mucosa and cancer tissues
a UMAP projection of fibroblasts from normal colon mucosa, colored by inferred cluster identity. b Proportions of the clusters in all fibroblasts. c UMAP projection of normal colon mucosa fibroblasts colored according to the patients (labeled P1 to P12, n = 12). d UMAP Feature plots of the expression distribution of classical fibroblast markers. e Heatmap showing the scaled expression of marker genes in each cluster of mucosal fibroblasts. f Violin plots showing selected distinct markers of clusters. g Heatmap of Pearson correlation coefficients between the normal colon mucosa fibroblast clusters. The dendrogram shows the inferred hierarchy of clusters according to the Pearson correlation coefficients of the average expression of marker genes among clusters. The color scale shows the Pearson correlation coefficient.
