Fig. 4: Integrated analysis of fibroblasts and myofibroblasts in human colonic mucosa and in human colon cancer tissues. | Communications Biology

Fig. 4: Integrated analysis of fibroblasts and myofibroblasts in human colonic mucosa and in human colon cancer tissues.

From: An integrated map of fibroblastic populations in human colon mucosa and cancer tissues

Fig. 4

a Comparison of colonic mucosal fibroblasts and colon cancer fibroblasts. UMAP projection of integrated analysis displayed separately by sample type. b Comparison of cell composition between mucosa and cancer tissues in each patient. c Table displays comparison of mean cell proportion of each cluster between mucosa and cancer tissue and number of significantly differentially expressed genes (padj < 0.05 & Log2FC > 1, decrease Increase: padj < 0.05 & Log2FC < -1). d Dot plot showing the scaled expression of signature genes for each cluster in mucosa and CRC. The colors representing each cluster in the color band correspond to those in Fig. 4a.

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