Fig. 2: Dynamics of circulating adaptive and innate T lymphocyte subsets during SARS-CoV-2 infection via aerosol and IT/IN route in NHPs. | Communications Biology

Fig. 2: Dynamics of circulating adaptive and innate T lymphocyte subsets during SARS-CoV-2 infection via aerosol and IT/IN route in NHPs.

From: The dynamics of γδ T cell responses in nonhuman primates during SARS-CoV-2 infection

Fig. 2

a Representative FACS plots of PBMC showing gating strategy for γδ T, CD4 T, CD8 T and MAIT cells. Quantification of T cell subset frequencies in peripheral blood as percentage of CD3 + T cells following SARS-CoV-2 infection in 8 animals per group either via aerosol (b) or IT/IN route (c) on 0, 1, 2, 3, 7, 14, 21, and 28 dpi. Absolute counts per μL of blood for γδ T, CD4 T, CD8 T and MAIT cells in aerosol (d) and IT/IN (e) route of infection. Individual values shown for each animal as symbols connected by lines for RMs (orange) and AGMs (blue). Comparisons of different time points with respect to d0 baseline data were done using repeated measures one-way ANOVA with Dunnett’s post hoc tests. Asterisks indicate significant differences between time points (*p < 0.05; **p < 0.01).

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