Fig. 7: Prioritization of top genes from all 129 genome-wide significant genes.
From: Rare variant analyses across multiethnic cohorts identify novel genes for refractive error
The top genes ranked by our prioritization schema. The figure contains the chromosome, basepair position, gene name, as well as the meta-analysis p-value and the individual cohort p-values for each gene. It also contains which test the given significant meta-analysis p-value refers to, and how many times the gene replicated in our internal analyses. Finally, it contains information regarding gene expression, whether the gene has a known ocular phenotype in mice or humans, overlap with the GWAS performed by Hysi et al., and the final overall prioritization score. This figure is based on results shown in Supplementary Data 26.
